The Big C premiered on SHO on August 16, 2010. Cathy Jamison is a reserved, stifled, Minneapolis schoolteacher who receives life changing news and decides, from that moment on, to make drastic, long-overdue adjustments to the way she is living her life. She's always been conservative and structured - the perfect suburban wife and mother - but Cathy is tired of being the sensible one. Now she wants to let her freak flag fly. For the first time in her life, she is going to make choices that suit her needs. Who says you can't eat dessert as an appetizer? Time is precious, and Cathy is grabbing life by the balls...